Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | F10 | P00742 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420044 | 1.00 | F2 (0.50) | F2F10HDAC6HDAC1MAPK1 | |
| SCHEMBL7420051 | 0.82 | F2 (0.55) | F2F10HDAC6HDAC1MAPK1 | |
| SCHEMBL4451691 | 0.82 | F2 (0.64) | F2F10HDAC6SMN1; SMN2KMT2A | |
| SCHEMBL4451687 | 0.82 | F2 (0.64) | F2F10HDAC6SMN1; SMN2KMT2A | |
| SCHEMBL7420054 | 0.80 | F2 (0.47) | F2F10MAPK1SMN1; SMN2RECQL | |
| SCHEMBL7097035 | 0.77 | F2 (0.68) | F2F10HDAC6MAPK1NPC1 | |
| SCHEMBL7416848 | 0.77 | F2 (0.68) | F2F10HDAC6MAPK1NPC1 | |
| SCHEMBL4443593 | 0.75 | F2 (0.83) | F2F10HDAC6NPC1RAB9A | |
| SCHEMBL4443592 | 0.75 | F2 (0.83) | F2F10HDAC6NPC1RAB9A | |
| SCHEMBL7415304 | 0.75 | F2 (0.59) | F2F10HDAC6SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248770-B1 | CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-19 | — | — | US | disclosed |