Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112678 | 0.87 | MAPT (0.55) | MAPTKMT2AMEN1ATMLMNA | |
| SCHEMBL7417960 | 0.87 | CA12 (0.62) | LMNANPSR1CA1CA2CA12 | |
| SCHEMBL7422657 | 0.84 | CA12 (0.46) | MAPTATMLMNACA1CA2 | |
| SCHEMBL310021 | 0.83 | ERN1 (0.58) | MAPTKMT2AMEN1ATMLMNA | |
| SCHEMBL31084750 | 0.83 | ERN1 (0.58) | MAPTKMT2AMEN1ATMLMNA | |
| SCHEMBL2316486 | 0.82 | CA1 (0.61) | MAPTKMT2AMEN1ATMLMNA | |
| SCHEMBL13611999 | 0.80 | NOTUM (0.42) | MAPTKMT2ALMNACA1CA2 | |
| SCHEMBL31614544 | 0.79 | MAPT (0.54) | MAPTKMT2AMEN1ATMLMNA | |
| SCHEMBL8890648 | 0.78 | ABCG2 (0.55) | MAPTKMT2AMEN1ATMLMNA | |
| SCHEMBL8890644 | 0.78 | ABCG2 (0.55) | MAPTKMT2AMEN1ATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995004046-A1 | COMPOUNDS AS PDE IV AND TNF INHIBITORS | RHONE-POULENC RORER LIMITED (GB) | 1995-02-09 | — | — | WO | disclosed |