Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.41 |
| ▸ | F10 | P00742 | 8/20 | 0.41 |
| ▸ | PLG | P00747 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408713 | 0.94 | F2 (0.39) | F2F10PLGMAPK1HDAC6 | |
| SCHEMBL7416844 | 0.93 | F2 (0.39) | F2F10PLGMAPK1HDAC6 | |
| SCHEMBL7413405 | 0.92 | F2 (0.40) | F2F10PLGMAPK1HDAC6 | |
| SCHEMBL7407838 | 0.91 | F2 (0.39) | F2F10PLGMAPK1HDAC6 | |
| SCHEMBL7100448 | 0.91 | F2 (0.39) | F2F10PLGMAPK1HDAC6 | |
| SCHEMBL7413828 | 0.88 | F2 (0.37) | F2F10PLGMAPK1 | |
| SCHEMBL7408746 | 0.86 | F2 (0.40) | F2F10PLGITGB3ITGA2B | |
| SCHEMBL7410854 | 0.86 | F2 (0.40) | F2F10PLGITGB3ITGA2B | |
| SCHEMBL7418083 | 0.86 | F2 (0.41) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7413698 | 0.85 | F2 (0.39) | F2F10PLGHDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-B1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-6248770-B1 | CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-19 | — | — | US | disclosed |