Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401657 | 0.77 | CHRM1 (0.48) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL7423076 | 0.76 | BRD4 (0.36) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL5519193 | 0.74 | BRD4 (0.45) | BRD4TDO2 | |
| SCHEMBL8406646 | 0.74 | CHRM2 (0.48) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL7415275 | 0.73 | BRD4 (0.44) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| Oxalic Acid SCHEMBL8405405 | 0.72 | CHRM2 (0.54) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL7420354 | 0.72 | CHRM2 (0.45) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL8874947 | 0.72 | CHRM2 (0.62) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL8402611 | 0.70 | CHRM1 (0.51) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL661974 | 0.70 | CHRM2 (0.84) | CHRM1CHRM2CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994373-A | COGNITION ACTIVATORS; GASTROINTESTINAL DISORDERS; PSYCHOLOGICAL DISORDERS | NOVO NORDISK A/S NOVO ALLE DK 2880 (DK) | 1999-11-30 | — | — | US | disclosed |
| EP-0835255-A1 | NOVEL SUBSTITUTED AZACYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997001555-A1 | NOVEL SUBSTITUTED AZACYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1997-01-16 | — | — | WO | disclosed |