Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL653965 | 0.94 | KMT2A (0.56) | KMT2APOLBMEN1FAAHMAPK1 | |
| SCHEMBL7420521 | 0.91 | KMT2A (0.47) | KMT2APOLBMEN1FAAHMAPK1 | |
| SCHEMBL7421199 | 0.88 | KMT2A (0.46) | KMT2APOLBMEN1FAAHMAPK1 | |
| SCHEMBL3190699 | 0.84 | KMT2A (0.59) | KMT2APOLBMEN1FAAHMAPK1 | |
| SCHEMBL11091388 | 0.84 | KMT2A (0.51) | KMT2APOLBMEN1FAAHMAPK1 | |
| SCHEMBL11083424 | 0.82 | KMT2A (0.53) | KMT2APOLBMEN1FAAHMAPK1 | |
| SCHEMBL19543494 | 0.81 | KMT2A (0.44) | KMT2APOLBNOD1L3MBTL1GAA | |
| SCHEMBL17662484 | 0.81 | KMT2A (0.44) | KMT2APOLBL3MBTL1GAAPLA2G2C | |
| SCHEMBL8904424 | 0.81 | KMT2A (0.44) | KMT2APOLBMEN1FAAHMAPK1 | |
| SCHEMBL27694937 | 0.81 | KMT2A (0.44) | KMT2APOLBNOD1DNM1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558487-B1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1998-10-07 | — | — | EP | disclosed |
| US-5328917-A | Aminoalkyl and phenyl substituted hydrogenated pyridines | NOVO NORDISK A/S (DK) | 1994-07-12 | — | — | US | disclosed |
| EP-0558487-A1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992001672-A1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-02-06 | — | — | WO | disclosed |