Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 9/20 | 0.54 |
| ▸ | CACNA1D | Q01668 | 9/20 | 0.54 |
| ▸ | CACNA1S | Q13698 | 9/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 9/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420762 | 1.00 | CACNA1F (0.54) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL27282494 | 0.89 | CACNA1F (0.48) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL2781025 | 0.88 | HIF1A (0.63) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL9262436 | 0.88 | HIF1A (0.63) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11008647 | 0.86 | CACNA1C (0.72) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11012400 | 0.85 | MEN1 (0.63) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11166123 | 0.83 | CACNA1F (0.54) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| Ethyl Chloride SCHEMBL2777613 | 0.83 | HIF1A (0.63) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL17237461 | 0.83 | CACNA1F (0.64) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL3940339 | 0.83 | CACNA1F (0.71) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126094-A1 | NEW 1,4-DIHYDROPYRIDINE ESTERS AND PREPARATION METHODS THEREOF AND DRUGS CONTAINING SAID ESTERS. | CERMOL SA (CH) | 1984-11-28 | — | — | EP | claimed |
| WO-1984002132-A1 | NEW 1,4-DIHYDROPYRIDINE ESTERS AND PREPARATION METHODS THEREOF AND DRUGS CONTAINING SAID ESTERS | CERMOL SA (CH) | 1984-06-07 | — | — | WO | claimed |
| EP-0126094-B1 | NEW 1,4-DIHYDROPYRIDINE ESTERS AND PREPARATION METHODS THEREOF AND DRUGS CONTAINING SAID ESTERS | CERMOL S.A. (CH) | 1990-06-20 | — | — | EP | disclosed |
| EP-0126094-A1 | NEW 1,4-DIHYDROPYRIDINE ESTERS AND PREPARATION METHODS THEREOF AND DRUGS CONTAINING SAID ESTERS. | CERMOL SA (CH) | 1984-11-28 | — | — | EP | disclosed |
| WO-1984002132-A1 | NEW 1,4-DIHYDROPYRIDINE ESTERS AND PREPARATION METHODS THEREOF AND DRUGS CONTAINING SAID ESTERS | CERMOL SA (CH) | 1984-06-07 | — | — | WO | disclosed |