Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 12/20 | 0.74 |
| ▸ | SSTR2 | P30874 | 9/20 | 0.68 |
| ▸ | GBA1 | P04062 | 7/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422102 | 0.90 | SSTR4 (0.76) | SSTR4SSTR2GBA1RAD52 | |
| SCHEMBL7421851 | 0.81 | SSTR4 (1.00) | SSTR4SSTR2GBA1RAD52 | |
| SCHEMBL7421016 | 0.81 | SSTR4 (0.71) | SSTR4SSTR2GBA1RAD52 | |
| Hydrochloric Acid SCHEMBL7423801 | 0.80 | SSTR4 (0.70) | SSTR4SSTR2GBA1RAD52 | |
| Bromide SCHEMBL7424764 | 0.80 | SSTR4 (0.98) | SSTR4SSTR2GBA1RAD52 | |
| SCHEMBL7429342 | 0.80 | SSTR4 (0.68) | SSTR4SSTR2GBA1RAD52 | |
| SCHEMBL7421605 | 0.78 | SSTR4 (1.00) | SSTR4SSTR2GBA1RAD52 | |
| SCHEMBL7426650 | 0.76 | SSTR4 (0.66) | SSTR4SSTR2GBA1RAD52 | |
| SCHEMBL7421638 | 0.76 | SSTR4 (0.58) | SSTR4SSTR2GBA1 | |
| SCHEMBL14813383 | 0.76 | SSTR4 (0.58) | SSTR4SSTR2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019050-B1 | USE OF SOMATOSTATIN AGONISTS AND ANTAGONISTS FOR TREATING DISEASES RELATED TO THE EYE | NOVO NORDISK AS (DK) | 2002-03-20 | — | — | EP | claimed |
| US-6159941-A | Use of somatostatin agonists and antagonists for treating diseases related to the eye | NOVO NORDISK A/S (DK) | 2000-12-12 | — | — | US | claimed |
| US-6127343-A | SELECTIVE, COMPETITIVE SOMATOSTATIN RECEPTOR LIGANDS OF NONPEPTIDE ORIGIN, FOR MEDIATING THE BIOLOGICAL EFFECT OF SOMATOSTATIN AGONISTS OR ANTAGONIST | NOVO NORDISK A/S (DK) | 2000-10-03 | — | — | US | claimed |
| EP-1019050-A1 | USE OF SOMATOSTATIN AGONISTS AND ANTAGONISTS FOR TREATING DISEASES RELATED TO THE EYE | NOVO NORDISK A/S (DK) | 2000-07-19 | — | — | EP | claimed |
| EP-0912551-A1 | SOMATOSTATIN AGONISTS AND ANTAGONISTS | NOVO NORDISK A/S (DK) | 1999-05-06 | — | — | EP | claimed |
| WO-1998058646-A1 | USE OF SOMATOSTATIN AGONISTS AND ANTAGONISTS FOR TREATING DISEASES RELATED TO THE EYE | NOVO NORDISK A/S (DK) | 1998-12-30 | — | — | WO | claimed |
| WO-1997043278-A1 | SOMATOSTATIN AGONISTS AND ANTAGONISTS | NOVO NORDISK A/S (DK) | 1997-11-20 | — | — | WO | claimed |
| EP-1019050-B1 | USE OF SOMATOSTATIN AGONISTS AND ANTAGONISTS FOR TREATING DISEASES RELATED TO THE EYE | NOVO NORDISK AS (DK) | 2002-03-20 | — | — | EP | disclosed |
| US-6159941-A | Use of somatostatin agonists and antagonists for treating diseases related to the eye | NOVO NORDISK A/S (DK) | 2000-12-12 | — | — | US | disclosed |
| US-6127343-A | SELECTIVE, COMPETITIVE SOMATOSTATIN RECEPTOR LIGANDS OF NONPEPTIDE ORIGIN, FOR MEDIATING THE BIOLOGICAL EFFECT OF SOMATOSTATIN AGONISTS OR ANTAGONIST | NOVO NORDISK A/S (DK) | 2000-10-03 | — | — | US | disclosed |
| EP-1019050-A1 | USE OF SOMATOSTATIN AGONISTS AND ANTAGONISTS FOR TREATING DISEASES RELATED TO THE EYE | NOVO NORDISK A/S (DK) | 2000-07-19 | — | — | EP | disclosed |
| EP-0912551-A1 | SOMATOSTATIN AGONISTS AND ANTAGONISTS | NOVO NORDISK A/S (DK) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998058646-A1 | USE OF SOMATOSTATIN AGONISTS AND ANTAGONISTS FOR TREATING DISEASES RELATED TO THE EYE | NOVO NORDISK A/S (DK) | 1998-12-30 | — | — | WO | disclosed |
| WO-1997043278-A1 | SOMATOSTATIN AGONISTS AND ANTAGONISTS | NOVO NORDISK A/S (DK) | 1997-11-20 | — | — | WO | disclosed |