Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412298 | 0.90 | GRM2 (0.82) | GRM2 | |
| SCHEMBL7421484 | 0.88 | GRM2 (1.00) | GRM2 | |
| SCHEMBL7422376 | 0.87 | GRM2 (1.00) | GRM2 | |
| SCHEMBL6732204 | 0.83 | GRM2 (0.78) | GRM2 | |
| SCHEMBL6732879 | 0.83 | GRM2 (0.82) | GRM2 | |
| SCHEMBL6727411 | 0.80 | GRM2 (0.78) | GRM2 | |
| SCHEMBL6734694 | 0.80 | GRM2 (0.78) | GRM2 | |
| SCHEMBL6728242 | 0.80 | GRM2 (1.00) | GRM2 | |
| SCHEMBL6732556 | 0.80 | GRM2 (0.73) | GRM2 | |
| SCHEMBL7417024 | 0.80 | GRM2 (1.00) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255735-A2 | PYRIDINE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-11-13 | — | — | EP | claimed |
| WO-2001056990-A2 | PYRIDINE DERIVATES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2001-08-09 | — | — | WO | claimed |
| EP-1255735-A2 | PYRIDINE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001056990-A2 | PYRIDINE DERIVATES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |