Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.50 |
| ▸ | LAP3 | P28838 | 2/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7623135 | 0.84 | ANPEP (0.53) | ANPEPLAP3SRCNPSR1MEN1 | |
| SCHEMBL1727266 | 0.79 | SRC (0.52) | ANPEPLAP3SRCNPSR1MEN1 | |
| SCHEMBL13783568 | 0.78 | ELANE (0.56) | ANPEPLAP3SRCNPSR1MEN1 | |
| SCHEMBL5958828 | 0.78 | SRC (0.50) | ANPEPLAP3SRCNPSR1MEN1 | |
| SCHEMBL7417923 | 0.77 | ANPEP (0.71) | ANPEPLAP3SRCNPSR1MEN1 | |
| SCHEMBL11281739 | 0.76 | SRC (0.54) | ANPEPLAP3SRCNPSR1MEN1 | |
| SCHEMBL28659355 | 0.76 | ANPEP (0.53) | ANPEPLAP3SRCNPSR1MEN1 | |
| SCHEMBL10832523 | 0.75 | SRC (0.58) | ANPEPLAP3SRCNPSR1MEN1 | |
| SCHEMBL131325 | 0.74 | NPSR1 (0.50) | ANPEPLAP3SRCNPSR1MEN1 | |
| Phenyl Dihydrogen Phosphate SCHEMBL11234180 | 0.74 | SRC (0.76) | ANPEPLAP3SRCTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9340820-B2 | Compounds and methods for protease detection | QUEEN'S UNIVERSITY OF BELFAST (GB) | 2016-05-17 | — | — | US | disclosed |
| US-5686419-A | SERINE PROTEASE INHIBITOR ANTICOAGULANTS | GEORGIA TECH RESEARCH CORP. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5543396-A | Proline phosphonate derivatives | GEORGIA TECH RESEARCH CORP. (US) | 1996-08-06 | — | — | US | disclosed |
| WO-1995029691-A1 | PROLINE PHOSPHONATE DERIVATIVES | GEORGIA TECH RESEARCH CORPORATION (US) | 1995-11-09 | — | — | WO | disclosed |