Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL732952 | 0.91 | NOTUM (0.45) | NOTUMKDM4EALDH1A1TDP1STS | |
| SCHEMBL4391166 | 0.91 | NOTUM (0.45) | NOTUMKDM4EALDH1A1TDP1STS | |
| SCHEMBL730884 | 0.86 | KDM4E (0.45) | NOTUMKDM4EALDH1A1TDP1STS | |
| SCHEMBL732876 | 0.85 | CA12 (0.56) | CNR2NOTUMKDM4EALDH1A1TDP1 | |
| SCHEMBL24736909 | 0.84 | STS (0.43) | SLC7A5CNR2NOTUMTDP1STS | |
| SCHEMBL30116304 | 0.84 | STS (0.43) | SLC7A5CNR2NOTUMTDP1STS | |
| SCHEMBL731011 | 0.81 | KAT6A (0.41) | NOTUMKDM4EALDH1A1TDP1STS | |
| SCHEMBL2720990 | 0.81 | CNR2 (0.46) | SLC7A5CNR2ATMNOTUMKDM4E | |
| SCHEMBL731053 | 0.80 | CA12 (0.45) | CA12CA1CA2CA9TSHR | |
| SCHEMBL10206864 | 0.80 | TSHR (0.44) | KDM4EALDH1A1STSGAAXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022584-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-03-21 | — | — | WO | disclosed |