Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 9/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | FNTA | P49354 | 6/20 | 0.40 |
| ▸ | FNTB | P49356 | 6/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423003 | 0.84 | FNTA (0.53) | PRMT5WDR77FNTAFNTBPGGT1B | |
| SCHEMBL8428326 | 0.83 | F10 (0.61) | F10F2 | |
| SCHEMBL27493161 | 0.82 | PRMT5 (0.44) | PRMT5WDR77F10F2FNTA | |
| SCHEMBL7418476 | 0.82 | PRMT5 (0.44) | PRMT5WDR77F10F2FNTA | |
| SCHEMBL7424116 | 0.82 | PRMT5 (0.44) | PRMT5WDR77F10F2FNTA | |
| SCHEMBL2332098 | 0.82 | F2 (0.39) | PRMT5WDR77F10F2FNTA | |
| SCHEMBL7422999 | 0.81 | SRC (0.48) | PRMT5WDR77F10F2FNTA | |
| SCHEMBL7419382 | 0.80 | FNTA (0.42) | PRMT5WDR77F10F2FNTA | |
| SCHEMBL27479463 | 0.80 | PRMT5 (0.43) | PRMT5WDR77F10F2KCNH2 | |
| SCHEMBL7424685 | 0.79 | FNTA (0.49) | F10FNTAFNTBPGGT1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040679-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-12-19 | — | — | WO | disclosed |