Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SLC9A3 | P48764 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11932029 | 1.00 | SLC6A2 (0.51) | SLC6A2SLC6A4MEN1KMT2ASLC9A3 | |
| SCHEMBL7417567 | 1.00 | SLC6A2 (0.51) | SLC6A2SLC6A4MEN1KMT2ASLC9A3 | |
| Hydrochloric Acid SCHEMBL7423941 | 0.99 | SLC6A2 (0.50) | SLC6A2SLC6A4MEN1KMT2ASLC9A3 | |
| Hydrochloric Acid SCHEMBL7423937 | 0.99 | SLC6A2 (0.50) | SLC6A2SLC6A4MEN1KMT2ASLC9A3 | |
| Hydrochloric Acid SCHEMBL7423946 | 0.99 | SLC6A2 (0.50) | SLC6A2SLC6A4MEN1KMT2ASLC9A3 | |
| SCHEMBL7419876 | 0.91 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC9A3SLC6A3CYP2D6 | |
| SCHEMBL7419877 | 0.91 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC9A3SLC6A3CYP2D6 | |
| SCHEMBL8639898 | 0.90 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC9A3SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL7408198 | 0.88 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC9A3SLC6A3CYP2D6 | |
| SCHEMBL7370489 | 0.86 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC9A3SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002494-A1 | BENZOCYCLOALKYLAMINE DERIVATIVES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-02-01 | — | — | WO | disclosed |