Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 16/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.34 |
| ▸ | FAP | Q12884 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175639 | 1.00 | DPP4 (0.35) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL7418737 | 0.82 | DPP7 (0.39) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL6492871 | 0.82 | DPP7 (0.39) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL6165300 | 0.82 | DPP7 (0.39) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL6171746 | 0.81 | DPP7 (0.44) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL7189181 | 0.78 | DPP4 (0.40) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL6174600 | 0.78 | DPP4 (0.40) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL6174604 | 0.78 | DPP4 (0.40) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL6167493 | 0.78 | DPP4 (0.47) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL7183513 | 0.78 | DPP4 (0.47) | DPP4DPP8DPP7DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254113-A1 | N-SUBSTITUTED 2-CYANOPYROLES AND -PYRROLINES WHICH ARE INHIBITORS OF THE ENZYME DPP-IV | NOVO NORDISK A/S (DK) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055105-A1 | N-SUBSTITUTED 2-CYANOPYROLES AND -PYRROLINES WHICH ARE INHIBITORS OF THE ENZYME DPP-IV | NOVO NORDISK A/S (DK) | 2001-08-02 | — | — | WO | disclosed |