Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.62 |
| ▸ | F2 | P00734 | 14/20 | 0.62 |
| ▸ | PROC | P04070 | 8/20 | 0.54 |
| ▸ | PLG | P00747 | 6/20 | 0.54 |
| ▸ | PLAT | P00750 | 6/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042796 | 0.90 | F10 (0.77) | F10F2PROCPLGPLAT | |
| SCHEMBL8029368 | 0.89 | F10 (0.77) | F10F2PROCPLGPLAT | |
| SCHEMBL8040050 | 0.86 | F10 (0.60) | F10F2PROCPLGPLAT | |
| SCHEMBL8029198 | 0.83 | F10 (0.75) | F10F2PROCPLGPLAT | |
| SCHEMBL7423245 | 0.83 | F10 (0.75) | F10F2PROCPLGPLAT | |
| SCHEMBL8029276 | 0.82 | F10 (0.74) | F10F2PROCPLGPLAT | |
| SCHEMBL8042774 | 0.80 | F10 (0.58) | F10F2PROCPLGPLAT | |
| SCHEMBL8039321 | 0.80 | F10 (0.57) | F10F2PROCPLGPLAT | |
| SCHEMBL8029360 | 0.79 | F10 (0.59) | F10F2PROCPLGPLAT | |
| SCHEMBL7479476 | 0.79 | F10 (0.57) | F10F2PROCPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740668-A1 | TETRACYCLIC DERIVATIVES, PROCESS OF PREPARATION AND USE | LABORATORIES GLAXO WELLCOME S.A. (FR) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995019978-A1 | TETRACYCLIC DERIVATIVES, PROCESS OF PREPARATION AND USE | LABORATOIRES GLAXO WELLCOME S.A. (FR) | 1995-07-27 | — | — | WO | disclosed |