Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426584 | 0.87 | GRM2 (0.56) | GRM2 | |
| SCHEMBL7422835 | 0.86 | GRM2 (0.71) | GRM2 | |
| SCHEMBL7427761 | 0.86 | GRM2 (0.65) | GRM2 | |
| SCHEMBL6738979 | 0.81 | GRM2 (0.58) | GRM2 | |
| SCHEMBL6732958 | 0.81 | GRM2 (0.65) | GRM2 | |
| SCHEMBL7420812 | 0.80 | GRM2 (0.66) | GRM2 | |
| SCHEMBL6728023 | 0.79 | GRM2 (0.54) | GRM2 | |
| SCHEMBL7422862 | 0.78 | GRM2 (0.78) | GRM2 | |
| SCHEMBL7421144 | 0.78 | GRM2 (0.63) | GRM2 | |
| SCHEMBL6733110 | 0.77 | GRM2 (0.64) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255735-A2 | PYRIDINE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-11-13 | — | — | EP | claimed |
| WO-2001056990-A2 | PYRIDINE DERIVATES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2001-08-09 | — | — | WO | claimed |