Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16512044 | 1.00 | MEN1 (0.53) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL31232357 | 0.97 | MEN1 (0.58) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL16512043 | 0.97 | MEN1 (0.58) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL4607133 | 0.90 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL6089218 | 0.88 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL365791 | 0.88 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL145212 | 0.88 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Tetraethylene Glycol SCHEMBL7173952 | 0.88 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Tetraethylene Glycol SCHEMBL22614781 | 0.88 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL8282624 | 0.88 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023295-B | Method for producing polyester polymers and polyester polymers obtainable therefrom | 苏尔寿管理有限公司 | 2024-03-22 | — | — | CN | claimed |
| US-20140107051-A1 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES | INSTYTUT FARMACEUTYCZNY (PL) | 2014-04-17 | — | — | US | disclosed |
| US-8623910-B2 | Isoflavones for treating mucopolysaccharidoses | INSTYTUT FARMACEUTYCZNY (PL) | 2014-01-07 | — | — | US | disclosed |
| US-20120190642-A1 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES | INSTYTUT FARMACEUTYCZNY (PL) | 2012-07-26 | — | — | US | disclosed |
| US-8178609-B2 | Isoflavones for treating mucopolysaccharidoses | INSTYTUT FARMACEUTYCZNY (PL) | 2012-05-15 | — | — | US | disclosed |
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107051-A1 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES | GAA, MAN2B1, IDUA | MEN1 1704/4885KMT2A 1912/4885TSHR 4634/4885 |
| US-20120190642-A1 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES | GAA, MAN2B1, IDUA | MEN1 1721/4885KMT2A 1734/4885TSHR 4669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.