Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17492502 | 0.90 | PARP1 (0.38) | SRCF2MAPTPARP1TRPV4 | |
| SCHEMBL525390 | 0.83 | SRC (0.50) | SRCF2CA12CA1CA2 | |
| SCHEMBL17458779 | 0.83 | SRC (0.47) | SRCF2CA12CA1CA2 | |
| SCHEMBL29469805 | 0.83 | SRC (0.47) | SRCF2CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL8986751 | 0.82 | SRC (0.49) | SRCF2CA12CA1CA2 | |
| SCHEMBL7867515 | 0.81 | SRC (0.44) | SRCF2CA12CA1CA2 | |
| SCHEMBL13696856 | 0.80 | F2 (0.44) | SRCF2CA12CA1CA2 | |
| SCHEMBL6359546 | 0.77 | SRC (0.53) | SRCF2CA12CA1CA2 | |
| SCHEMBL6535829 | 0.74 | KMT2A (0.58) | SRCF2CA1CA2KMT2A | |
| SCHEMBL5759503 | 0.73 | SRC (0.49) | SRCSLC13A5MAPTHDAC4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101519429-B | Solid phase method for synchronizing Argatroban | SHENZHEN HYBIO PHARMACEUTICAL | 2012-07-25 | — | — | CN | claimed |
| CN-101519429-A | Solid phase method for synchronizing Argatroban | SHENZHEN HYBIO ENGINEERING CO | 2009-09-02 | — | — | CN | claimed |
| CN-101519429-B | Solid phase method for synchronizing Argatroban | SHENZHEN HYBIO PHARMACEUTICAL | 2012-07-25 | — | — | CN | disclosed |
| CN-101519429-A | Solid phase method for synchronizing Argatroban | SHENZHEN HYBIO ENGINEERING CO | 2009-09-02 | — | — | CN | disclosed |
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |
| US-5552410-A | 1,2,3,4,-tetrahydroquinoline-8-sulphonic acid chlorides and acids, their preparation and their use as synthetic intermediates | SYNTHELABO (FR) | 1996-09-03 | — | — | US | disclosed |
| US-5552410-A | 1,2,3,4,-tetrahydroquinoline-8-sulphonic acid chlorides and acids, their preparation and their use as synthetic intermediates | SYNTHELABO (FR) | 1996-09-03 | — | — | US | disclosed |
| CN-1076928-A | 1-[2-arylsulfonyl amino)-and the 1-oxoethyl] piperidine derivative and preparation and the application in treatment | SYNTHELABO (FR) | 1993-10-06 | — | — | CN | disclosed |