Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | LGMN | Q99538 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2189798 | 0.76 | MAPT (0.56) | MAPTPKMALDH1A1SLC18A2KMT2A | |
| SCHEMBL2189791 | 0.76 | MAPT (0.56) | MAPTPKMALDH1A1SLC18A2KMT2A | |
| SCHEMBL2189794 | 0.76 | MAPT (0.56) | MAPTPKMALDH1A1SLC18A2KMT2A | |
| SCHEMBL7414046 | 0.74 | — | — | |
| SCHEMBL2189830 | 0.74 | SLC6A4 (0.43) | MAPTPKM | |
| SCHEMBL2189838 | 0.74 | SLC6A4 (0.43) | MAPTPKM | |
| SCHEMBL2189833 | 0.74 | SLC6A4 (0.43) | MAPTPKM | |
| SCHEMBL2188885 | 0.73 | MAPT (0.42) | MAPTPKMALDH1A1NPC1SLC18A2 | |
| SCHEMBL2188875 | 0.73 | MAPT (0.42) | MAPTPKMALDH1A1NPC1SLC18A2 | |
| SCHEMBL2190204 | 0.73 | MAPT (0.42) | MAPTPKMALDH1A1NPC1SLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789415-A | Azacyclic-heterocyclic compounds as angiotension II receptor antagonists | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| WO-1995002596-A1 | AZACYCLIC-HETEROCYCLIC COMPOUNDS AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-01-26 | — | — | WO | disclosed |