Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432140 | 0.86 | GAA (0.42) | TSHRCTSK | |
| SCHEMBL7432135 | 0.86 | GAA (0.42) | TSHRCTSK | |
| SCHEMBL4095492 | 0.85 | CA14 (0.46) | CA12CA14CA2DGAT1CA1 | |
| SCHEMBL7431200 | 0.85 | CA14 (0.46) | CA12CA14CA2DGAT1CA1 | |
| SCHEMBL2139570 | 0.83 | CA12 (0.37) | CA12CA14CA2RECQLCA1 | |
| SCHEMBL6901600 | 0.83 | CA12 (0.37) | CA12CA14CA2RECQLCA1 | |
| SCHEMBL20928615 | 0.82 | CA14 (0.45) | CA12CA14TET2RECQLTSHR | |
| SCHEMBL30887609 | 0.81 | CA12 (0.36) | CA12CA14CA2RECQLDGAT1 | |
| SCHEMBL29196454 | 0.81 | CA12 (0.36) | CA12CA14CA2RECQLDGAT1 | |
| SCHEMBL18911163 | 0.79 | CA12 (0.39) | CA12CA14CA2RECQLDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |