Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 5/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10471456 | 0.78 | MEN1 (0.55) | CACNA1CHIF1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4637034 | 0.78 | CYP1A2 (0.50) | CACNA1CHIF1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10873574 | 0.77 | MAPT (0.56) | CACNA1CHIF1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10469171 | 0.76 | CYP1A2 (0.58) | CACNA1CHIF1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27671464 | 0.75 | CACNA1F (0.42) | CACNA1CHIF1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL16189736 | 0.73 | TSHR (0.66) | CACNA1CHIF1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9262436 | 0.73 | HIF1A (0.63) | CACNA1CHIF1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10680441 | 0.73 | HIF1A (0.52) | CACNA1CHIF1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2781025 | 0.73 | HIF1A (0.63) | CACNA1CHIF1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9827844 | 0.72 | CACNA1C (0.43) | CACNA1CHIF1ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126094-A1 | NEW 1,4-DIHYDROPYRIDINE ESTERS AND PREPARATION METHODS THEREOF AND DRUGS CONTAINING SAID ESTERS. | CERMOL SA (CH) | 1984-11-28 | — | — | EP | claimed |
| WO-1984002132-A1 | NEW 1,4-DIHYDROPYRIDINE ESTERS AND PREPARATION METHODS THEREOF AND DRUGS CONTAINING SAID ESTERS | CERMOL SA (CH) | 1984-06-07 | — | — | WO | claimed |