Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.83 |
| ▸ | F10 | P00742 | 10/20 | 0.53 |
| ▸ | PLG | P00747 | 7/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7981433 | 0.99 | F2 (0.82) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7430218 | 0.92 | F2 (0.71) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7433344 | 0.92 | F2 (0.70) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL8027337 | 0.91 | F2 (1.00) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7489333 | 0.91 | F2 (0.68) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7979427 | 0.90 | F2 (0.70) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7424400 | 0.90 | F2 (0.68) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8027136 | 0.90 | F2 (0.98) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7425435 | 0.87 | F2 (0.66) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL6633799 | 0.87 | F2 (1.00) | F2F10PLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | claimed |
| EP-1071669-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2001-01-31 | — | — | EP | claimed |
| WO-1999054313-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-28 | — | — | WO | claimed |
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |