Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 11/20 | 0.47 |
| ▸ | SSTR2 | P30874 | 6/20 | 0.47 |
| ▸ | GBA1 | P04062 | 13/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419465 | 0.96 | SSTR4 (0.45) | SSTR4SSTR2GBA1MEN1ALDH1A1 | |
| SCHEMBL7476252 | 0.87 | SSTR4 (0.61) | SSTR4SSTR2GBA1MEN1ALDH1A1 | |
| SCHEMBL7429330 | 0.87 | SSTR4 (0.56) | SSTR4SSTR2GBA1MEN1ALDH1A1 | |
| SCHEMBL7477561 | 0.85 | GBA1 (0.45) | SSTR4SSTR2GBA1MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7483543 | 0.84 | GBA1 (0.44) | SSTR4SSTR2GBA1MEN1ALDH1A1 | |
| SCHEMBL7421016 | 0.81 | SSTR4 (0.71) | SSTR4SSTR2GBA1MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7423801 | 0.81 | SSTR4 (0.70) | SSTR4SSTR2GBA1MEN1ALDH1A1 | |
| SCHEMBL7421208 | 0.77 | SSTR4 (0.33) | SSTR4SSTR2GBA1RAD52 | |
| SCHEMBL8189126 | 0.76 | SSTR4 (0.32) | SSTR4SSTR2GBA1MEN1KMT2A | |
| SCHEMBL7484674 | 0.75 | GBA1 (0.57) | SSTR4SSTR2GBA1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019050-B1 | USE OF SOMATOSTATIN AGONISTS AND ANTAGONISTS FOR TREATING DISEASES RELATED TO THE EYE | NOVO NORDISK AS (DK) | 2002-03-20 | — | — | EP | claimed |
| US-6159941-A | Use of somatostatin agonists and antagonists for treating diseases related to the eye | NOVO NORDISK A/S (DK) | 2000-12-12 | — | — | US | claimed |
| US-6127343-A | SELECTIVE, COMPETITIVE SOMATOSTATIN RECEPTOR LIGANDS OF NONPEPTIDE ORIGIN, FOR MEDIATING THE BIOLOGICAL EFFECT OF SOMATOSTATIN AGONISTS OR ANTAGONIST | NOVO NORDISK A/S (DK) | 2000-10-03 | — | — | US | claimed |
| EP-1019050-A1 | USE OF SOMATOSTATIN AGONISTS AND ANTAGONISTS FOR TREATING DISEASES RELATED TO THE EYE | NOVO NORDISK A/S (DK) | 2000-07-19 | — | — | EP | claimed |
| EP-0912551-A1 | SOMATOSTATIN AGONISTS AND ANTAGONISTS | NOVO NORDISK A/S (DK) | 1999-05-06 | — | — | EP | claimed |
| WO-1998058646-A1 | USE OF SOMATOSTATIN AGONISTS AND ANTAGONISTS FOR TREATING DISEASES RELATED TO THE EYE | NOVO NORDISK A/S (DK) | 1998-12-30 | — | — | WO | claimed |
| WO-1997043278-A1 | SOMATOSTATIN AGONISTS AND ANTAGONISTS | NOVO NORDISK A/S (DK) | 1997-11-20 | — | — | WO | claimed |