Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 10/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391285 | 0.89 | CACNA1B (0.72) | CACNA1BNPC1RAB9ASIGMAR1TP53 | |
| SCHEMBL7385922 | 0.85 | CACNA1B (0.67) | CACNA1BNPC1RAB9ASIGMAR1TP53 | |
| SCHEMBL7385284 | 0.84 | CACNA1B (0.66) | CACNA1BNPC1RAB9ASIGMAR1TP53 | |
| SCHEMBL7393738 | 0.84 | CACNA1B (0.66) | CACNA1BNPC1RAB9ASIGMAR1TP53 | |
| SCHEMBL7393847 | 0.84 | CACNA1B (0.65) | CACNA1BNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL7390816 | 0.84 | CACNA1B (0.65) | CACNA1BNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL7391219 | 0.83 | CACNA1B (0.65) | CACNA1BNPC1RAB9ASIGMAR1TP53 | |
| SCHEMBL7380925 | 0.83 | CACNA1B (0.70) | CACNA1BNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7388358 | 0.83 | CACNA1B (0.64) | CACNA1BNPC1RAB9ASIGMAR1SMN1; SMN2 | |
| SCHEMBL7424073 | 0.83 | CACNA1B (0.53) | CACNA1BNPC1RAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251919-B1 | ADMINISTERING ANILINE DERIVATIVE FOR THERAPY OF PAIN | WARNER-LAMBERT | 2001-06-26 | — | — | US | claimed |
| WO-1999043658-A1 | HETEROCYCLIC SUBSTITUTED ANILINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-09-02 | — | — | WO | claimed |
| US-6251919-B1 | ADMINISTERING ANILINE DERIVATIVE FOR THERAPY OF PAIN | WARNER-LAMBERT | 2001-06-26 | — | — | US | disclosed |
| WO-1999043658-A1 | HETEROCYCLIC SUBSTITUTED ANILINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-09-02 | — | — | WO | disclosed |