Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422826 | 0.78 | HTR2A (0.38) | HTR2AHTR2CHTR2B | |
| SCHEMBL1577842 | 0.77 | HTR2A (0.41) | HTR2AHTR2CHTR2B | |
| SCHEMBL2390258 | 0.77 | HTR2C (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL15653605 | 0.77 | HTR2A (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL7427186 | 0.75 | KDM1A (0.39) | HTR2AHTR2CHTR2B | |
| SCHEMBL909812 | 0.74 | CHRNA7 (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL6607744 | 0.74 | HTR2A (0.31) | HTR2AHTR2CHTR2B | |
| SCHEMBL2770556 | 0.74 | HTR2A (0.31) | HTR2AHTR2CHTR2B | |
| SCHEMBL5526874 | 0.74 | KDM1A (0.38) | HTR2AHTR2CHTR2B | |
| SCHEMBL6634855 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958280-A1 | ARYLPIPERIDINOPROPANOL AND ARYLPIPERAZINOPROPANOL DERIVATIVES AND PHARMACEUTICALS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1999-11-24 | — | — | EP | disclosed |
| WO-1999023072-A1 | ARYLPIPERIDINOPROPANOL AND ARYLPIPERAZINOPROPANOL DERIVATIVES AND PHARMACEUTICALS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1999-05-14 | — | — | WO | disclosed |