Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.51 |
| ▸ | STK17B | O94768 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11934906 | 0.91 | PRSS1 (0.48) | STK17ASTK17BMAPTALDH1A1PRSS1 | |
| SCHEMBL11748511 | 0.91 | MAPT (0.52) | STK17AMAPTALDH1A1PRSS1F2 | |
| SCHEMBL3005414 | 0.86 | TAAR1 (0.46) | STK17ASTK17BMAPTALDH1A1TAAR1 | |
| SCHEMBL2064760 | 0.85 | MAPT (0.57) | MAPTALDH1A1TAAR1 | |
| Hydrochloric Acid SCHEMBL3027696 | 0.84 | TAAR1 (0.44) | STK17ASTK17BMAPTALDH1A1PRSS1 | |
| SCHEMBL9155154 | 0.82 | APP (0.52) | STK17AMAPTALDH1A1PRSS1F2 | |
| SCHEMBL13876474 | 0.80 | MAPT (0.43) | STK17ASTK17BMAPTALDH1A1PRSS1 | |
| SCHEMBL178398 | 0.80 | MAPT (0.74) | STK17AMAPTALDH1A1PRSS1TAAR1 | |
| SCHEMBL11348193 | 0.80 | STK17A (0.55) | STK17ASTK17BMAPTALDH1A1PRSS1 | |
| SCHEMBL1072934 | 0.79 | MAPT (0.73) | MAPTALDH1A1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1012147-A2 | O-SUBSTITUTED HYDROXYCUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999006387-A2 | O-SUBSTITUTED HYDROXYCUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-02-11 | — | — | WO | disclosed |