Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6732943 | 0.91 | GRM2 (0.81) | GRM2 | |
| SCHEMBL5273246 | 0.91 | GRM2 (0.60) | GRM2 | |
| SCHEMBL6731857 | 0.89 | GRM2 (0.79) | GRM2 | |
| SCHEMBL6735265 | 0.89 | GRM2 (0.71) | GRM2 | |
| SCHEMBL6732644 | 0.88 | GRM2 (0.81) | GRM2 | |
| SCHEMBL6738387 | 0.87 | GRM2 (0.83) | GRM2 | |
| SCHEMBL6739453 | 0.85 | GRM2 (1.00) | GRM2 | |
| SCHEMBL6733905 | 0.84 | GRM2 (1.00) | GRM2 | |
| SCHEMBL6727974 | 0.83 | GRM2 (1.00) | GRM2 | |
| SCHEMBL6730996 | 0.83 | GRM2 (1.00) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255735-A2 | PYRIDINE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001056990-A2 | PYRIDINE DERIVATES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |