Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABAT | P80404 | 1/20 | 0.52 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.49 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3069393 | 0.98 | ABAT (0.53) | ABATERCC1ERCC4FFAR1ALDH1A1 | |
| Benzene SCHEMBL27714747 | 0.98 | ABAT (0.53) | ABATERCC1ERCC4FFAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2006870 | 0.98 | ABAT (0.53) | ABATERCC1ERCC4FFAR1ALDH1A1 | |
| SCHEMBL41828 | 0.98 | ABAT (0.53) | ABATERCC1ERCC4FFAR1ALDH1A1 | |
| SCHEMBL7785939 | 0.98 | ABAT (0.53) | ABATERCC1ERCC4FFAR1ALDH1A1 | |
| SCHEMBL1330698 | 0.98 | ABAT (0.53) | ABATERCC1ERCC4FFAR1ALDH1A1 | |
| SCHEMBL4091646 | 0.95 | ABAT (0.52) | ABATERCC1ERCC4FFAR1ALDH1A1 | |
| SCHEMBL2573295 | 0.95 | ABAT (0.52) | ABATERCC1ERCC4FFAR1ALDH1A1 | |
| Methane SCHEMBL5247717 | 0.95 | ABAT (0.52) | ABATERCC1ERCC4FFAR1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27375923 | 0.95 | ABAT (0.52) | ABATERCC1ERCC4FFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951466-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | Elan Pharmaceuticals, Inc. (US) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998028268-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS AS β-AMYLOID PEPTIDE RELEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 1998-07-02 | — | — | WO | disclosed |