SCHEMBL742607

SCHEMBL742607

C=C[CH]C1OCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7861842 1.00
SCHEMBL9781388 0.88
SCHEMBL19523376 0.73 TDP1 (0.42)
SCHEMBL305072 0.73
SCHEMBL8109972 0.67
SCHEMBL2789528 0.66
Methylene Chloride SCHEMBL28274707 0.65 TDP1 (0.35)
Ethylene Glycol SCHEMBL7588413 0.63 TSHR (0.33)
Allyl Alcohol SCHEMBL9234665 0.63 TSHR (0.47)
SCHEMBL7563785 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240083850-A1 NOVEL LAPPACONITINE DERIVATIVE AND USE THEREOF QGENETICS CO., LTD. (KR) 2024-03-14 US claimed
EP-4119543-A2 NOVEL LAPPACONITINE DERIVATIVE AND USE THEREOF QGenetics Co., Ltd. (KR) 2023-01-18 EP claimed
CN-115244034-A Novel lappaconitine derivative and application thereof 可嘉妮提株式会社 2022-10-25 CN claimed
US-8778961-B2 O-methylated rapamycin derivatives for alleviation and inhibition of lymphoproliferative disorders THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2014-07-15 US claimed
US-8759370-B2 O-methylated rapamycin derivatives for alleviation and inhibition of lymphoproliferative disorders THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2014-06-24 US claimed
EP-2073856-B1 COATED IMPLANT ARTIC GMBH (DE) 2014-03-05 EP claimed
US-8569332-B2 O-methylated rapamycin derivatives for alleviation and inhibition of lymphoproliferative disorders THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2013-10-29 US claimed
US-8492026-B2 Rechargeable battery SAMSUNG SDI CO., LTD. (KR) 2013-07-23 US claimed
EP-2446886-A1 Autophagy regulators and the uses thereof in the treatment of collagen VI defective Muscular Dystrophies Fondazione Telethon (IT) 2012-05-02 EP claimed
US-8138344-B2 Process for the preparation of rapamycin derivatives NOVARTIS AG (CH) 2012-03-20 US claimed
CN-1061322-A The safe of benzoic acid derivative class weed killer herbicide MONSANTO CO (US) 1992-05-27 CN claimed
US-5051514-A Complexing boranes and imidazoles CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1991-09-24 US claimed
CN-1052768-A The safe handling of imidazolidinone weedicide MONSANTO CO (US) 1991-07-10 CN claimed
EP-0432987-A2 Fungicidal organoborane imidazole compounds and intermediates therefor CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1991-06-19 EP claimed
US-4983589-A Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1991-01-08 US claimed
EP-0163607-B1 MEANS FOR THE PROTECTION OF CULTURE PLANTS AGAINST THE PHYTOTOXIC ACTION OF CHLORACETANILIDE HERBICIDES CIBA-GEIGY AG (CH) 1989-11-08 EP claimed
CN-87102879-A Benzhydryl compounds as herbicide antidotes 1987-10-28 CN claimed
EP-0190105-A2 Herbicidal agent CIBA-GEIGY AG (CH) 1986-08-06 EP claimed
EP-0163607-A2 Means for the protection of culture plants against the phytotoxic action of chloracetanilide herbicides CIBA-GEIGY AG (CH) 1985-12-04 EP claimed
US-4225334-A USED WITH HERBICIDES CIBA-GEIGY CORPORATION (US) 1980-09-30 US claimed