Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295182 | 0.87 | HRH3 (0.57) | CNR2KMT2AHTTNPC1RAB9A | |
| SCHEMBL2294060 | 0.87 | HRH3 (0.57) | CNR2KMT2AHTTNPC1RAB9A | |
| SCHEMBL27889560 | 0.86 | CNR2 (0.53) | CNR2KMT2AHTTMEN1NPC1 | |
| SCHEMBL2082396 | 0.86 | DRD3 (0.56) | CNR2KMT2AMEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL27891813 | 0.85 | CNR2 (0.52) | CNR2KMT2AHTTMEN1NPC1 | |
| SCHEMBL2294445 | 0.85 | CNR2 (0.70) | CNR2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL322849 | 0.85 | CNR2 (0.70) | CNR2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2294401 | 0.85 | CNR2 (0.70) | CNR2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2293379 | 0.84 | CNR2 (0.55) | CNR2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2295902 | 0.84 | CNR2 (0.55) | CNR2KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000006559-A1 | REDUCED DIPEPTIDE ANALOGUES AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |