Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.48 |
| ▸ | CPN1 | P15169 | 5/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28212852 | 1.00 | CYP2C9 (0.50) | CYP2C9CYP2C19HIF1ASHBGCPN1 | |
| Cyclohexane SCHEMBL16341926 | 1.00 | CYP2C9 (0.50) | CYP2C9CYP2C19HIF1ASHBGCPN1 | |
| SCHEMBL9133567 | 1.00 | CYP2C9 (0.50) | CYP2C9CYP2C19HIF1ASHBGCPN1 | |
| Cyclohexane SCHEMBL4365734 | 1.00 | CYP2C9 (0.50) | CYP2C9CYP2C19HIF1ASHBGCPN1 | |
| Cyclohexane SCHEMBL253223 | 1.00 | CYP2C9 (0.50) | CYP2C9CYP2C19HIF1ASHBGCPN1 | |
| SCHEMBL506450 | 1.00 | CYP2C9 (0.50) | CYP2C9CYP2C19HIF1ASHBGCPN1 | |
| Cyclohexane SCHEMBL6631080 | 1.00 | CYP2C9 (0.50) | CYP2C9CYP2C19HIF1ASHBGCPN1 | |
| SCHEMBL12804034 | 1.00 | CYP2C9 (0.50) | CYP2C9CYP2C19HIF1ASHBGCPN1 | |
| SCHEMBL13711836 | 1.00 | CYP2C9 (0.50) | CYP2C9CYP2C19HIF1ASHBGCPN1 | |
| SCHEMBL134162 | 0.98 | CYP2C9 (0.49) | CYP2C9CYP2C19HIF1ASHBGCPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049695-A1 | 2-PHENYL SUBSTITUTED IMIDAZOTRIAZINONES AS PHOSPHODIESTERASE INHIBITORS | BAYER AG (DE) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999024433-A1 | 2-PHENYL SUBSTITUTED IMIDAZOTRIAZINONES AS PHOSPHODIESTERASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-05-20 | — | — | WO | disclosed |