⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1752603 | 1.00 | — | — | |
| SCHEMBL566257 | 1.00 | — | — | |
| SCHEMBL7470586 | 0.69 | — | — | |
| SCHEMBL3193971 | 0.69 | — | — | |
| SCHEMBL10693878 | 0.69 | — | — | |
| SCHEMBL6119995 | 0.69 | — | — | |
| SCHEMBL7850668 | 0.69 | — | — | |
| SCHEMBL8814679 | 0.69 | — | — | |
| SCHEMBL7850665 | 0.69 | — | — | |
| SCHEMBL6852724 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 526 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020233534-A1 | ANTIBODY-DRUG CONJUGATE PREPARATION, PREPARATION METHOD THEREFOR AND USE THEREOF | 百奥泰生物制药股份有限公司 (CN) | 2020-11-26 | — | — | WO | claimed |
| CN-111939267-A | Antibody-drug conjugate preparation, preparation method and application | 百奥泰生物制药股份有限公司 | 2020-11-17 | — | — | CN | claimed |
| US-20110195898-A1 | TREATMENT OF ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT USING GNRH-I ANALOGS AND ONE OR MORE OF ACETYLCHOLINESTERASE INHIBITORS AND NMDA RECEPTOR ANTAGONISTS | VOYAGER PHARMACEUTICAL CORPORATION (US) | 2011-08-11 | — | — | US | claimed |
| US-7947839-B2 | Heterocyclic-substituted bis-1,8 naphthalimide compounds, antibody drug conjugates, and methods of use | GENENTECH, INC. (US) | 2011-05-24 | — | — | US | claimed |
| WO-2011032159-A1 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT | META COMESTICS, LLC (US) | 2011-03-17 | — | — | WO | claimed |
| US-20110002866-A1 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT | LUBIT BEVERLY W | 2011-01-06 | — | — | US | claimed |
| EP-1838715-B1 | METHOD FOR THE PREPARATION OF MAYTANSINOID ESTERS | IMMUNOGEN INC (US) | 2010-10-27 | — | — | EP | claimed |
| US-20090270390-A1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA (SE) | 2009-10-29 | — | — | US | claimed |
| US-20090233926-A1 | 2-BENZIMIDAZOLYL-6-MORPHOLINO-4-PIPERIDIN-4-YLPYRIMIDINE DERIVATIVES AS PI3K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA (SE) | 2009-09-17 | — | — | US | claimed |
| EP-1451209-A4 | TETRA-,PENTA-,HEXA- AND HEPTAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY | ABBOTT LAB (US) | 2009-06-03 | — | — | EP | claimed |
| US-4885276-A | IMMUNOSUPPRESSIVE AGENTS WITH DECREASED TOXICITY | MERCK & CO., INC. (US) | 1989-12-05 | — | — | US | claimed |
| WO-1989007450-A1 | LHRH ANALOGS | ABBOTT LABORATORIES (US) | 1989-08-24 | — | — | WO | claimed |
| WO-1989007451-A1 | REDUCED SIZE LHRH ANALOGS | ABBOTT LABORATORIES (US) | 1989-08-24 | — | — | WO | claimed |
| EP-0328090-A2 | LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | claimed |
| EP-0328089-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | claimed |
| US-4798823-A | IMMUNOSUPPRESSIVE AGENTS | MERCK & CO., INC. (US) | 1989-01-17 | — | — | US | claimed |
| EP-0296122-A2 | Cyclosporins and their use as pharmaceuticals | SANDOZ AG (CH) | 1988-12-21 | — | — | EP | claimed |
| EP-0149581-B1 | COMPOSITIONS CONTAINING OLIGO-MURAMYLPEPTIDES AND THEIR APPLICATION, IN PARTICULAR FOR THE ACTIVATION OF MACROPHAGES | ANVAR Agence Nationale de Valorisation de la Recherche (FR) | 1987-07-22 | — | — | EP | claimed |
| EP-0188214-A2 | Novel growth hormone-releasing peptides and method of treating mammals therewith | The Administrators of The Tulane University Educational Fund (US) | 1986-07-23 | — | — | EP | claimed |
| EP-0149581-A2 | Compositions containing oligo-muramylpeptides and their application, in particular for the activation of macrophages | ANVAR Agence Nationale de Valorisation de la Recherche (FR) | 1985-07-24 | — | — | EP | claimed |