SCHEMBL7428372

SCHEMBL7428372

CC(C)(C)SC[C@H](NC(=O)C(CS)Cc1ccccc1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MME P08473 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7325439 0.87 MME (0.73) MME
SCHEMBL7325442 0.87 MME (0.73) MME
SCHEMBL7325434 0.87 MME (0.73) MME
SCHEMBL7319230 0.87 MME (0.65) MME
SCHEMBL9566687 0.87 MME (0.65) MME
SCHEMBL7319224 0.87 MME (0.65) MME
SCHEMBL9566691 0.87 MME (0.65) MME
SCHEMBL7319219 0.87 MME (0.65) MME
SCHEMBL7444467 0.85 ACE (0.81)
SCHEMBL7431829 0.85 ACE (0.81)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5262436-A Administering; enzyme inhibitor SCHERING CORPORATION (US) 1993-11-16 US disclosed
US-5061710-A Atrial natriuretic factors SCHERING CORPORATION (US) 1991-10-29 US disclosed
US-4929641-A DIURETICS, ANGIOTENSIN CONVERTING ENZYMES SCHERING CORPORATION (US) 1990-05-29 US disclosed
US-4801609-A Mercapto-acylamino acid antihypertensives SCHERING CORPORATION (US) 1989-01-31 US disclosed