Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.51 |
| ▸ | ACE | P12821 | 5/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435407 | 1.00 | DPP4 (0.61) | DPP4TAAR1ALDH1A1KDM4EDPP7 | |
| SCHEMBL6442160 | 0.92 | DPP4 (0.69) | DPP4TAAR1ALDH1A1KDM4EDPP7 | |
| SCHEMBL7423021 | 0.92 | DPP4 (0.69) | DPP4TAAR1ALDH1A1KDM4EDPP7 | |
| SCHEMBL6437760 | 0.91 | DPP4 (0.64) | DPP4TAAR1ALDH1A1KDM4EDPP7 | |
| SCHEMBL6436557 | 0.86 | DPP4 (0.61) | DPP4ALDH1A1KDM4EDPP7DPP8 | |
| SCHEMBL6782785 | 0.78 | DPP4 (0.69) | DPP4DPP7DPP8ACEACE2 | |
| SCHEMBL6438881 | 0.78 | DPP4 (0.69) | DPP4DPP7DPP8ACEACE2 | |
| SCHEMBL7423200 | 0.78 | DPP4 (0.69) | DPP4DPP7DPP8ACEACE2 | |
| SCHEMBL6439098 | 0.77 | DPP4 (0.64) | DPP4DPP7DPP8ACEACE2 | |
| SCHEMBL6436770 | 0.77 | DPP4 (0.46) | DPP4ALDH1A1KDM4EACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975600-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | Akzo Nobel N.V. (NL) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998047876-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | AKZO NOBEL N.V. (NL) | 1998-10-29 | — | — | WO | disclosed |