Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901749 | 0.82 | EGLN1 (0.47) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL7432682 | 0.81 | CA14 (0.45) | TSHRALDH1A1MAPTLMNAPTGS2 | |
| SCHEMBL7429510 | 0.81 | CA14 (0.45) | TSHRALDH1A1MAPTLMNAPTGS2 | |
| SCHEMBL10771721 | 0.79 | SMN1; SMN2 (0.43) | TSHRALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL19174359 | 0.78 | TSHR (0.41) | TSHRALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL7431053 | 0.77 | CYP2D6 (0.36) | TSHRALDH1A1MAPTTDP1CYP2D6 | |
| SCHEMBL2139570 | 0.74 | CA12 (0.37) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL6901600 | 0.74 | CA12 (0.37) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL18726371 | 0.74 | TSHR (0.45) | TSHRALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL807266 | 0.74 | TSHR (0.45) | TSHRALDH1A1MAPTTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | claimed |
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |