Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429328 | 1.00 | EP300 (0.43) | EP300FAAHCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28324880 | 0.98 | EP300 (0.46) | EP300FAAHCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9799758 | 0.95 | EP300 (0.36) | EP300CYP2C19CYP2D6 | |
| SCHEMBL9799762 | 0.95 | EP300 (0.36) | EP300CYP2C19CYP2D6 | |
| Acrylic Acid Methyl Ester SCHEMBL28055940 | 0.86 | TSHR (0.36) | EP300CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL29117775 | 0.85 | EP300 (0.43) | EP300FAAHCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28359391 | 0.84 | EP300 (0.42) | EP300FAAHCYP1A2BLMHSD17B10 | |
| SCHEMBL28835407 | 0.83 | EP300 (0.44) | EP300FAAHCYP1A2BLMHSD17B10 | |
| SCHEMBL28717969 | 0.83 | EP300 (0.44) | EP300FAAHCYP1A2BLMHSD17B10 | |
| SCHEMBL15156757 | 0.83 | EP300 (0.44) | EP300FAAHCYP1A2BLMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332955-A | Preparation method of cefditoren pivoxil intermediate | 深圳六合六医疗器械有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-115724854-A | Preparation method of cefotaxime sodium double-side chain impurity | 深圳鼎邦生物科技有限公司 | 2023-03-03 | — | — | CN | disclosed |
| US-5939410-A | AN ANTIBIOTIC COMPRISING A HYDROLYSABLE ESTERS IN VIVO | HOFFMANN-LA ROCHE INC. (US) | 1999-08-17 | — | — | US | disclosed |
| CN-1184110-A | 1 -carba -(dethia) -cephalosporin derivatives | HOFFMANN LA ROCHE (CH) | 1998-06-10 | — | — | CN | disclosed |
| EP-0809644-A1 | 4-SUBSTITUTED CEPHEM DERIVATIVES AS ELASTASE INHIBITORS | PHARMACIA & UPJOHN S.p.A. (IT) | 1997-12-03 | — | — | EP | disclosed |
| WO-1997022609-A1 | 4-SUBSTITUTED CEPHEM DERIVATIVES AS ELASTASE INHIBITORS | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-06-26 | — | — | WO | disclosed |
| CN-1028430-C | Process for preparing new derivatives of 1-dethia 2-thiacephalosporanic acids | ROUSSEL UCLAF (FR) | 1995-05-17 | — | — | CN | disclosed |
| CN-1028236-C | Process for preparing acyl derivatives | HOFFMANN LA ROCHE (CH) | 1995-04-19 | — | — | CN | disclosed |
| CN-1021226-C | PREPARATION FOR ACYL DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1993-06-16 | — | — | CN | disclosed |
| CN-1036958-A | The preparation method of acyl derivative | HOFFMANN LA ROCHE (CH) | 1989-11-08 | — | — | CN | disclosed |
| CN-87105204-A | ACYL DERIVATIVES | — | 1988-06-29 | — | — | CN | disclosed |
| CN-87107753-A | New substituted cephalosporin sulfones as anti-inflammatory and antidegenerative agent | — | 1988-06-29 | — | — | CN | disclosed |
| CN-86105905-A | Process for the preparation of cephalosporin nucleus derivatives and their use in medicaments | — | 1987-07-29 | — | — | CN | disclosed |