Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.55 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.44 |
| ▸ | LAP3 | P28838 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GNPAT | O15228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429984 | 1.00 | MME (0.55) | MMESLC7A5ALDH1A1MAPTENPEP | |
| SCHEMBL31752207 | 1.00 | MME (0.55) | MMESLC7A5ALDH1A1MAPTENPEP | |
| SCHEMBL7822916 | 1.00 | MME (0.55) | MMESLC7A5ALDH1A1MAPTENPEP | |
| SCHEMBL29870736 | 0.97 | MME (0.53) | MMESLC7A5ALDH1A1MAPTENPEP | |
| SCHEMBL29350942 | 0.95 | MME (0.51) | MMESLC7A5ALDH1A1MAPTENPEP | |
| SCHEMBL30193318 | 0.94 | MME (0.50) | MMESLC7A5ALDH1A1ENPEP | |
| SCHEMBL17803183 | 0.94 | MME (0.50) | MMESLC7A5ALDH1A1ENPEP | |
| SCHEMBL29885518 | 0.92 | MME (0.60) | MMESLC7A5ALDH1A1ENPEPGNPAT | |
| SCHEMBL29414957 | 0.92 | MME (0.51) | MMESLC7A5ALDH1A1MAPTLAP3 | |
| SCHEMBL29630563 | 0.92 | MME (0.51) | MMESLC7A5ALDH1A1MAPTLAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133484-A2 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | AstraZeneca AB (SE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000005223-A2 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | ASTRAZENECA AB (SE) | 2000-02-03 | — | — | WO | disclosed |