Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.66 |
| ▸ | HPGD | P15428 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.66 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.66 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.66 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.66 |
| ▸ | GGT1 | P19440 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyrocetyl SCHEMBL26164 | 0.89 | MAPK1 (1.00) | MAPK1KDM4EHSD17B10HPGDALDH1A1 | |
| Dipyrocetyl SCHEMBL29508594 | 0.89 | MAPK1 (1.00) | MAPK1KDM4EHSD17B10HPGDALDH1A1 | |
| Dipyrocetyl SCHEMBL11121474 | 0.88 | MAPK1 (0.96) | MAPK1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL10912314 | 0.88 | KDM4E (0.64) | MAPK1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL7172325 | 0.86 | MAPK1 (0.81) | MAPK1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL29603325 | 0.85 | MAPT (0.59) | MAPK1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL152563 | 0.85 | MAPT (0.59) | MAPK1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL2238585 | 0.85 | MAPK1 (0.59) | MAPK1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL9191986 | 0.84 | MAPT (0.58) | MAPK1KDM4EHSD17B10HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL4229730 | 0.84 | MAPT (0.58) | MAPK1KDM4EHSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192135-A2 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076970-A2 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |