Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.81 |
| ▸ | CCR1 | P32246 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491898 | 1.00 | HRH3 (1.00) | HRH3MEN1KMT2ACCR1 | |
| SCHEMBL492046 | 1.00 | HRH3 (1.00) | HRH3MEN1KMT2ACCR1 | |
| SCHEMBL491855 | 1.00 | HRH3 (1.00) | HRH3MEN1KMT2ACCR1 | |
| SCHEMBL491772 | 0.99 | HRH3 (1.00) | HRH3MEN1KMT2ACCR1 | |
| SCHEMBL5289503 | 0.98 | HRH3 (0.98) | HRH3MEN1KMT2ACCR1 | |
| SCHEMBL491793 | 0.95 | HRH3 (1.00) | HRH3MEN1KMT2ACCR1 | |
| SCHEMBL8545622 | 0.94 | HRH3 (0.98) | HRH3MEN1KMT2ACCR1 | |
| SCHEMBL2443711 | 0.93 | HRH3 (0.95) | HRH3MEN1KMT2A | |
| SCHEMBL2443304 | 0.93 | HRH3 (0.95) | HRH3MEN1KMT2A | |
| SCHEMBL2445934 | 0.92 | HRH3 (0.93) | HRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100503-A2 | NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H 3?-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | SOCIETE CIVILE BIOPROJET (FR) | 2001-05-23 | — | — | EP | claimed |
| WO-2000006254-A2 | NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H3-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | SOCIETE CIVILE BIOPROJET (FR) | 2000-02-10 | — | — | WO | claimed |