Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7436806 | 0.99 | KMT2A (0.52) | KMT2AMEN1CYP2D6CHRM2CHRM1 | |
| SCHEMBL7436473 | 0.90 | MEN1 (0.48) | KMT2AMEN1CYP2D6CHRM2CHRM1 | |
| SCHEMBL7438122 | 0.90 | MEN1 (0.48) | KMT2AMEN1CYP2D6CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL7437435 | 0.89 | MEN1 (0.50) | KMT2AMEN1CYP2D6CHRM2CHRM1 | |
| SCHEMBL7440554 | 0.87 | MEN1 (0.65) | KMT2AMEN1CYP2D6CHRM2CHRM1 | |
| SCHEMBL7436750 | 0.86 | MEN1 (0.47) | KMT2AMEN1CYP2D6CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL7428326 | 0.86 | MEN1 (0.67) | KMT2AMEN1CYP2D6CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL7444488 | 0.85 | MEN1 (0.49) | KMT2AMEN1CYP2D6CHRM2CHRM1 | |
| SCHEMBL7433900 | 0.84 | MEN1 (0.46) | KMT2AMEN1CYP2D6CHRM2CHRM1 | |
| SCHEMBL7433633 | 0.84 | MEN1 (0.49) | KMT2AMEN1CYP2D6CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037848-A | Aryl-cycloalkyl-alkanolamines for treatment of epilepsy | WASHINGTON UNIVERSITY (US) | 1991-08-06 | — | — | US | disclosed |
| US-4988710-A | Anticonvulsants, anticholinergic agents, aryl-cycloalkanolamines | WASHINGTON UNIVERSITY (US) | 1991-01-29 | — | — | US | disclosed |
| US-4945097-A | THERAPY FOR ANOXIA, HYPOXIA, OR ISCHEMIA | G. D. SEARLE & CO. (US) | 1990-07-31 | — | — | US | disclosed |