Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.65 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448354 | 0.86 | HDAC2 (0.67) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| SCHEMBL747792 | 0.84 | HDAC1 (0.65) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| SCHEMBL212652 | 0.80 | HDAC1 (0.80) | HDAC1HDAC2HDAC3NCOR2HDAC8 | |
| SCHEMBL460273 | 0.79 | HDAC2 (0.62) | HDAC1HDAC2HDAC3HDAC6HDAC8 | |
| SCHEMBL675168 | 0.78 | HDAC1 (0.76) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| SCHEMBL29603842 | 0.78 | HDAC1 (0.76) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| SCHEMBL13053955 | 0.78 | NPC1 (0.62) | HDAC1HDAC2HDAC3 | |
| SCHEMBL1060512 | 0.77 | HDAC1 (0.67) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| SCHEMBL447989 | 0.77 | HDAC1 (0.62) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| SCHEMBL23746024 | 0.77 | HDAC1 (0.90) | HDAC1HDAC2HDAC3NCOR2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2429987-A2 | AMIDE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Korea Research Institute Of Chemical Technology (KR) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010131922-A2 | AMIDE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-11-18 | — | — | WO | disclosed |