Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 15/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522834 | 0.84 | CYP3A4 (0.40) | KDM4EKMT2A | |
| SCHEMBL21916708 | 0.81 | KDM4E (0.39) | KDM4EKMT2A | |
| SCHEMBL2837316 | 0.78 | KMT2A (0.40) | HDAC4KDM4EKMT2A | |
| SCHEMBL13127864 | 0.76 | KMT2A (0.39) | KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL1226520 | 0.76 | KMT2A (0.39) | KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL1226467 | 0.76 | KMT2A (0.39) | KDM4EKMT2A | |
| SCHEMBL10296046 | 0.76 | KDM4E (0.39) | KDM4EKMT2A | |
| SCHEMBL7808381 | 0.76 | KMT2A (0.39) | KDM4EKMT2A | |
| Bromide SCHEMBL16057314 | 0.76 | KMT2A (0.39) | KDM4EKMT2A | |
| SCHEMBL9613199 | 0.76 | KDM4E (0.38) | HDAC4MMP1MMP13KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147078-A1 | ACETYLENIC (BETA)-SULFONAMIDO AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS | American Cyanamid Company (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000044711-A1 | ACETYLENIC $G(b)-SULFONAMIDO AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |