Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433352 | 0.90 | ACE (0.53) | ACE | |
| SCHEMBL7423494 | 0.82 | ACE (0.62) | ACE | |
| SCHEMBL7424221 | 0.82 | ACE (0.62) | ACE | |
| SCHEMBL7423498 | 0.82 | ACE (0.62) | ACE | |
| SCHEMBL10431400 | 0.80 | ACE (0.64) | ACE | |
| SCHEMBL9525352 | 0.79 | ACE (0.73) | ACE | |
| SCHEMBL9526161 | 0.79 | ACE (0.62) | ACE | |
| SCHEMBL9525346 | 0.79 | ACE (0.73) | ACE | |
| SCHEMBL9526737 | 0.79 | ACE (0.73) | ACE | |
| SCHEMBL9525339 | 0.79 | ACE (0.73) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711884-A | HYPOTENSIVE AGENTS; ANGIOTENSIN ENZYME INHIBITING ACTIVITY | E. R. SQUIBB & SONS, INC. (US) | 1987-12-08 | — | — | US | disclosed |
| EP-0120728-A1 | Thiazine and thiazepine containing compounds | E.R. Squibb & Sons, Inc. (US) | 1984-10-03 | — | — | EP | disclosed |