Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439469 | 0.88 | ELANE (1.00) | ELANE | |
| SCHEMBL7544451 | 0.88 | ELANE (0.78) | ELANE | |
| SCHEMBL7436961 | 0.85 | ELANE (1.00) | ELANE | |
| SCHEMBL7434328 | 0.79 | ELANE (1.00) | ELANE | |
| SCHEMBL7436488 | 0.77 | ELANE (1.00) | ELANE | |
| SCHEMBL8866440 | 0.76 | ELANE (0.67) | ELANE | |
| SCHEMBL8866035 | 0.76 | ELANE (0.88) | ELANE | |
| SCHEMBL7438739 | 0.74 | ELANE (1.00) | ELANE | |
| SCHEMBL9083706 | 0.67 | ELANE (0.56) | ELANE | |
| SCHEMBL7299773 | 0.67 | ELANE (0.81) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5306818-A | Treating degenerative diseases such as emphysema, rheumatoid arthritis and pancreatitis | STERLING WINTHROP INC. (US) | 1994-04-26 | — | — | US | claimed |
| EP-0483928-A1 | 2-Saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use | STERLING WINTHROP INC. (US) | 1992-05-06 | — | — | EP | claimed |