Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 16/20 | 0.72 |
| ▸ | MME | P08473 | 12/20 | 0.72 |
| ▸ | XIAP | P98170 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440309 | 1.00 | ACE (0.72) | ACEMMEXIAP | |
| SCHEMBL7449038 | 1.00 | ACE (0.72) | ACEMMEXIAP | |
| SCHEMBL7433496 | 1.00 | ACE (0.72) | ACEMMEXIAP | |
| SCHEMBL7437629 | 1.00 | ACE (0.72) | ACEMMEXIAP | |
| SCHEMBL7437620 | 1.00 | ACE (0.72) | ACEMMEXIAP | |
| SCHEMBL8837745 | 0.95 | ACE (0.73) | ACEMME | |
| SCHEMBL7341241 | 0.95 | ACE (0.73) | ACEMME | |
| SCHEMBL8968300 | 0.91 | ACE (0.69) | ACEMMEXIAP | |
| SCHEMBL7439947 | 0.90 | ACE (0.59) | ACEMMEXIAP | |
| SCHEMBL7439940 | 0.90 | ACE (0.59) | ACEMMEXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026719-A1 | MERCAPTO-AMIDE DERIVATIVES USEFUL AS NEUTRAL ENDOPEPTIDASE AND ACE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |