Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435487 | 0.85 | HDAC3 (0.49) | MAPTALDH1A1GAACA12CA9 | |
| SCHEMBL1994885 | 0.78 | NAMPT (0.77) | MAPTNAMPTALDH1A1MEN1KMT2A | |
| SCHEMBL7433057 | 0.77 | MAPT (0.52) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7430590 | 0.76 | GAA (0.53) | MAPTALDH1A1GAA | |
| SCHEMBL7431684 | 0.76 | GAA (0.52) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL802338 | 0.75 | GAA (0.72) | MAPTNAMPTALDH1A1MEN1KMT2A | |
| SCHEMBL7432797 | 0.75 | SMN1; SMN2 (0.51) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9843022 | 0.75 | GAA (0.76) | MAPTNAMPTALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5194020 | 0.74 | GAA (0.70) | MAPTNAMPTALDH1A1MEN1KMT2A | |
| SCHEMBL27425392 | 0.74 | TSHR (0.75) | MAPTNAMPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |