Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.63 |
| ▸ | F10 | P00742 | 3/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424278 | 0.93 | F2 (0.65) | F2F10PRSS1 | |
| SCHEMBL7430323 | 0.84 | F2 (0.65) | F2F10 | |
| SCHEMBL7423757 | 0.81 | F2 (0.61) | F2F10PRSS1 | |
| SCHEMBL7424650 | 0.81 | F2 (0.54) | F2F10 | |
| SCHEMBL7423194 | 0.79 | F2 (0.67) | F2F10 | |
| SCHEMBL7430809 | 0.76 | F2 (0.63) | F2F10 | |
| SCHEMBL7425222 | 0.76 | F10 (0.47) | F2F10PRSS1 | |
| SCHEMBL7429823 | 0.74 | F10 (0.60) | F2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL34433766 | 0.71 | F2 (1.00) | F2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL28553434 | 0.71 | F2 (1.00) | F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107954-A1 | 2-OXO-$i(2H)-QUINOLINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012479-A1 | 2-OXO-2H-QUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-03-09 | — | — | WO | disclosed |