Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amantadine SCHEMBL7437971 | 0.82 | EPHX2 (0.38) | — | |
| Amantadine SCHEMBL7437952 | 0.82 | EPHX2 (0.38) | — | |
| SCHEMBL21533007 | 0.80 | — | — | |
| SCHEMBL7435839 | 0.80 | — | — | |
| SCHEMBL11376033 | 0.77 | — | — | |
| SCHEMBL7434809 | 0.76 | — | — | |
| SCHEMBL10449486 | 0.72 | — | — | |
| SCHEMBL7432563 | 0.72 | — | — | |
| SCHEMBL26742185 | 0.68 | TSHR (0.53) | TSHR | |
| SCHEMBL11695310 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | claimed |
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |