Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 15/20 | 0.74 |
| ▸ | CASP2 | P42575 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322692 | 0.98 | EPHX1 (0.78) | EPHX1CASP2 | |
| SCHEMBL11323835 | 0.98 | EPHX1 (0.78) | EPHX1CASP2 | |
| SCHEMBL8319523 | 0.98 | EPHX1 (0.78) | EPHX1CASP2 | |
| SCHEMBL25277323 | 0.98 | EPHX1 (0.78) | EPHX1CASP2 | |
| SCHEMBL8395449 | 0.98 | EPHX1 (0.78) | EPHX1CASP2 | |
| SCHEMBL25228937 | 0.98 | EPHX1 (0.78) | EPHX1CASP2 | |
| SCHEMBL25228539 | 0.98 | EPHX1 (0.78) | EPHX1CASP2 | |
| SCHEMBL24285430 | 0.98 | EPHX1 (0.78) | EPHX1CASP2 | |
| SCHEMBL8397082 | 0.98 | EPHX1 (0.78) | EPHX1CASP2 | |
| SCHEMBL11316399 | 0.98 | EPHX1 (0.78) | EPHX1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468470-B1 | Benzimidazoles, medicaments containing them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-04-16 | — | — | EP | claimed |
| US-4959092-A | Substituted phenyl (or pyridyl) urea compound and herbicidal composition containing the same as active ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1990-09-25 | — | — | US | claimed |
| EP-0293839-A2 | Substituted phenyl (or pyridyl) urea compound and herbicidal composition containing the same as active ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1988-12-07 | — | — | EP | claimed |
| JP-1153672-A | — | — | None | — | — | JP | disclosed |
| EP-4444300-A2 | INHIBITORS OF MENIN-MLL INTERACTION | Bala Therapeutics, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| EP-4446310-A1 | METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND | Asahi Kasei Kabushiki Kaisha (JP) | 2024-10-16 | — | — | EP | disclosed |
| CN-118382612-A | Method for producing blocked isocyanate compound and method for producing isocyanate compound | 旭化成株式会社 | 2024-07-23 | — | — | CN | disclosed |
| WO-2023106377-A1 | METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND | 旭化成株式会社 | 2023-06-15 | — | — | WO | disclosed |
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |
| US-20200299577-A1 | INHIBITION OF METAL CORROSION IN AQUEOUS MEDIA USING A POLYUREA FORMULATION | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2020-09-24 | — | — | US | disclosed |
| WO-2018128720-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-07-12 | — | — | WO | disclosed |
| US-5594003-A | HYPOTENSIVE AGENTS | DR. KARL THOMAE GMBH (DE) | 1997-01-14 | — | — | US | disclosed |
| US-5591762-A | HYPOTENSIVE AGENTS | DR. KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5587393-A | ANGIOTENSIN ANTAGONIST USEFUL IN TREATING HYPERTENSION | DR. KARL THOMAE GMBH (DE) | 1996-12-24 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| US-5459147-A | Angeotensin-antagonistic effects; hypotensive, antiischemic, and antidiabetic agents, treating glaucoma | DR. KARL THOMAE GMBH (DE) | 1995-10-17 | — | — | US | disclosed |
| US-5385925-A | Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1995-01-31 | — | — | US | disclosed |
| US-4959092-A | Substituted phenyl (or pyridyl) urea compound and herbicidal composition containing the same as active ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1990-09-25 | — | — | US | disclosed |
| JP-H01153672-A | SUBSTITUTED PHENYLUREA DERIVATIVE AND HERBICIDE CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT | MITSUBISHI KASEI CORP | 1989-06-15 | — | — | JP | disclosed |
| EP-0293839-A2 | Substituted phenyl (or pyridyl) urea compound and herbicidal composition containing the same as active ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1988-12-07 | — | — | EP | disclosed |