Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6412531 | 0.97 | TSHR (0.31) | TSHR | |
| SCHEMBL6416898 | 0.97 | TSHR (0.31) | TSHR | |
| SCHEMBL3844575 | 0.97 | TSHR (0.31) | TSHR | |
| SCHEMBL19428195 | 0.97 | — | — | |
| Trimethylammonium SCHEMBL28785814 | 0.90 | — | — | |
| SCHEMBL12506153 | 0.88 | — | — | |
| SCHEMBL19428206 | 0.88 | — | — | |
| Oxirane SCHEMBL28861124 | 0.87 | — | — | |
| Benzene SCHEMBL28874925 | 0.87 | — | — | |
| Oxalic Acid SCHEMBL28847398 | 0.84 | GAA (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230219-A1 | AROMATIC SULFONS HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. Searle & Co. (US) | 2002-08-14 | — | — | EP | disclosed |
| EP-1157021-A1 | SULFAMATO HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2001-11-28 | — | — | EP | disclosed |
| EP-1042290-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-2000050396-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2000-08-31 | — | — | WO | disclosed |
| WO-2000046221-A1 | SULFAMATO HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2000-08-10 | — | — | WO | disclosed |
| WO-1999025687-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 1999-05-27 | — | — | WO | disclosed |
| US-4294974-A | Hydrophilic silicone compounds and contact lenses containing polymers thereof | AMERICAN OPTICAL CORPORATION (US) | 1981-10-13 | — | — | US | disclosed |
| US-4261875-A | Contact lenses containing hydrophilic silicone polymers | AMERICAN OPTICAL CORPORATION (US) | 1981-04-14 | — | — | US | disclosed |