Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.87 |
| ▸ | LTA4H | P09960 | 2/20 | 0.65 |
| ▸ | ACE | P12821 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3063381 | 0.93 | MME (1.00) | MMELTA4HACE | |
| SCHEMBL8166946 | 0.93 | MME (1.00) | MMELTA4HACE | |
| SCHEMBL10952078 | 0.93 | MME (1.00) | MMELTA4HACE | |
| SCHEMBL10954948 | 0.93 | MME (1.00) | MMELTA4HACE | |
| SCHEMBL4371284 | 0.91 | MME (0.72) | MMELTA4HACE | |
| SCHEMBL8861571 | 0.88 | MME (0.84) | MMELTA4H | |
| SCHEMBL8861641 | 0.88 | MME (0.84) | MMELTA4H | |
| SCHEMBL8861574 | 0.88 | MME (0.84) | MMELTA4H | |
| SCHEMBL7320628 | 0.87 | MME (0.93) | MME | |
| SCHEMBL6173139 | 0.86 | MME (0.86) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262436-A | Administering; enzyme inhibitor | SCHERING CORPORATION (US) | 1993-11-16 | — | — | US | disclosed |
| US-5061710-A | Atrial natriuretic factors | SCHERING CORPORATION (US) | 1991-10-29 | — | — | US | disclosed |
| US-4929641-A | DIURETICS, ANGIOTENSIN CONVERTING ENZYMES | SCHERING CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4801609-A | Mercapto-acylamino acid antihypertensives | SCHERING CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |